Publications
Research documents freely given. Use what helps.
Cross-System Medicine and Global Health
139 pages. Medical hypotheses, clinical protocols, global health analysis.
All findings are correlations requiring validation.
776 KB · January 2026
Clinical Protocols & Guidelines
Evidence-based clinical resources derived from literature synthesis, available for healthcare providers.
22q11.2DS Clinical Management Guide for Primary Care
Practical guidance for primary care physicians managing 22q11.2DS patients. Covers screening recommendations, red flags, specialist referral criteria, and coordination of care.
22q11.2DS Autoimmune Screening Protocol
Evidence-based screening protocol for early detection of autoimmune conditions in 22q11.2DS. Includes timing, tests, interpretation guidance, and follow-up pathways.
Pre-Registered Hypotheses
All hypotheses are publicly registered before validation attempts, ensuring scientific rigor and preventing post-hoc rationalization. These predictions await testing in appropriate cohorts.
Outcome: New autoimmune diagnosis (SLE, ITP, thyroiditis, JIA)
Falsification: OR < 1.5 in adequately powered cohort
Status: Pre-registered, seeking validation cohort
Outcome: Conversion to psychosis spectrum disorder
Falsification: AUC < 0.60 in validation cohort
Status: Pre-registered, seeking validation cohort
Outcome: IBD prevalence vs. matched controls
Falsification: Prevalence ratio < 2.0
Status: Pre-registered, epidemiological data needed
Our Approach to Publication
We believe in transparency. Rather than claiming finished work before it exists, we share our hypotheses openly. When manuscripts are completed and submitted, they will be posted here with full documentation.
Pre-registering hypotheses before testing prevents "p-hacking" and post-hoc rationalization. It ensures that our predictions are genuine forecasts, not explanations retrofitted to data. If a hypothesis fails validation, we will report that failure transparently.